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Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives

Received: 20 February 2014     Published: 30 March 2014
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Abstract

An easy preparation of enaminonitrile derivatives, obtained by using a mixture of triethyl orthoformate and piperidine in DMF solution, and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiation led to high conversion and shorter reaction times.

Published in Modern Chemistry (Volume 2, Issue 1)
DOI 10.11648/j.mc.20140201.11
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Pyrazolopyrimidines, Enamines, Aminopyrazole, Microwave Irradiation

References
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Cite This Article
  • APA Style

    Hanadi Yousef. Medrasi, Abdellatif Mohamed Salaheldin. (2014). Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives. Modern Chemistry, 2(1), 1-5. https://doi.org/10.11648/j.mc.20140201.11

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    ACS Style

    Hanadi Yousef. Medrasi; Abdellatif Mohamed Salaheldin. Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives. Mod. Chem. 2014, 2(1), 1-5. doi: 10.11648/j.mc.20140201.11

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    AMA Style

    Hanadi Yousef. Medrasi, Abdellatif Mohamed Salaheldin. Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives. Mod Chem. 2014;2(1):1-5. doi: 10.11648/j.mc.20140201.11

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  • @article{10.11648/j.mc.20140201.11,
      author = {Hanadi Yousef. Medrasi and Abdellatif Mohamed Salaheldin},
      title = {Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives},
      journal = {Modern Chemistry},
      volume = {2},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.mc.20140201.11},
      url = {https://doi.org/10.11648/j.mc.20140201.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20140201.11},
      abstract = {An easy preparation of enaminonitrile derivatives, obtained by using a mixture of triethyl orthoformate and piperidine in DMF solution, and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiation led to high conversion and shorter reaction times.},
     year = {2014}
    }
    

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    T1  - Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives
    AU  - Hanadi Yousef. Medrasi
    AU  - Abdellatif Mohamed Salaheldin
    Y1  - 2014/03/30
    PY  - 2014
    N1  - https://doi.org/10.11648/j.mc.20140201.11
    DO  - 10.11648/j.mc.20140201.11
    T2  - Modern Chemistry
    JF  - Modern Chemistry
    JO  - Modern Chemistry
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.mc.20140201.11
    AB  - An easy preparation of enaminonitrile derivatives, obtained by using a mixture of triethyl orthoformate and piperidine in DMF solution, and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiation led to high conversion and shorter reaction times.
    VL  - 2
    IS  - 1
    ER  - 

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Author Information
  • Department of Chemistry, Sciences faculty for Girls, King Abdulaziz University, Jeddah, Jeddah, KSA

  • Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, KSA

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